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Organic chemistry tools for understanding biology

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Chemical Tools for Profiling Methylation PTMs

January 25, 2021March 7, 2024 Benjamin Emenike

Abstract Lysine methylation is one of the most important post-translational modifications (PTMs) of proteins as it regulates various biological processes including cell growth, division, gene

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Secondary amine selective Petasis (SASP) Bioconjugation

January 25, 2021March 7, 2024 Benjamin Emenike

Abstract Selective modification of proteins enables synthesis of antibody-drug conjugates, cellular drug delivery and construction of new materials. Many groups have developed methods for selective

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Recent News

April 22nd 2025 Congratulations to Lyndsey, Patricia, and Angele on their successful PhD defenses! Further congratulations to Min and Tuan for both receiving highest honors for their undergraduate thesis defense

February 21st 2025 Congratulations to all of our second years for passing their candidacy exams!

August 27th 2024 Congratulations to Riley for receiving a BDCI T32 fellowship, John for winning a 2024 ARCS award, and Monika for being named a 2025 ACS Women Chemistry Committee (ACS-WCC) Rising Star Award. We also wish Dr. Ranjana the best as she begins her independent career an assistant professor at IIT!

June 1st 2024 Congrats to all for the following publications since 2024 began: Ben and Samrat (Nat. Commun.), Angele, Victor, and Patrick (Angew. Chem.), Ben and Patrick (JACS), Ben and Sophia (Angew. Chem.), Rachel, Raju, and John (Chem. Sci.), Zach and John (Synlett)

May 3rd 2024 Departmental awards! Congrats to Sophia (Undergraduate Excellence in Research Award, John (2nd year Excellence in Research Award), Lyndsey (Outstanding Citizen Award), and Ben (Best Dissertation Award)

April 20th 2024 Congratulation to Dr. Benjamin Emenike on a successful thesis defense! You will do great with your post-doc with Christopher Chang at Princeton

February 6th 2024 Congratulations to Dr. Rachel Wills on a successful thesis defense! You'll do great at Abbvie!

November 21st 2023 We are happy to welcome our new first year graduate students: Ana, Ankita, Bao, and Riley! Keep an eye out for their exciting work in the future!

September 13th 2023 Lyndsey, John, and Rose's recent paper was the most viewed Org. Lett. article for August 2023!

August 1st 2023 Congrats Ben&Julia, Victor&Angele, Daniel&Patrick, and Rachel&Jonathan&Sophia&Patrick on their publications in JACS, Angew. Chem., Nature Comm., and Chem. Sci., respectfully :) very busy month in the Raj lab!

July 21st 2023 Congrats to John and Andy (Wuest lab) on receiving a BDCI trainee seed grant. See the news release here!

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