Independent Publications

Kuei-Chien Tang, Jian Cao, Lisa M. Boatner, Linwei Li, Jonathan Farhi, Kendall N. Houk, Jennifer Spangle, Keriann M. Backus, Monika Raj. Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angewandte Chemie International Edition. 2021. doi:10.1002/anie.202112107.

Adebomi, V., Sriram, M., Streety, X., Raj, M. Metal-Free Selective Modification of Secondary Amides: Application in Late-Stage Diversification of Peptides. Org. Lett., 2021, 23, 6189–6193.

Nwajiobi, O.; Mahesh, S.; Streety, X.; Raj, M. Selective Triazenation Reaction (star) of Secondary Amines for Tagging Monomethyl Lysine Post‐translational ModificationsAngew. Chem. Int. Ed. 2021133 (13), 7420–7428.

Tang, K. C.; Raj, M. One‐Step Azolation Strategy for Site‐ and Chemo‐Selective Labeling of Proteins with Mass‐Sensitive Probes. Angew. Chem. Int. Ed202160 (4), 1797–1805.

Wills, R.; Adeobmi, V.; Raj, M. Site selective peptide macrocyclizationChemBioChem. 2020 (Invited Review article)

Wills, R.; Adeobmi, V.; Raj, M. Peptide cyclization at high concentrationSynlett 2020,31, 1537-1542. (Invited Review article

Mahesh Sriram, Victor Adeobmi, and Monika RajBioinspired nitroalkylation for selective protein modification and peptide stapling.Angew. Chem. Int. Ed. 2020, 59, 2793-2801.

Yonnette E. Sim, Ogonna Nwajiobi, Sriram Mahesh, Ryan D. Cohen, Mikhail Y. Reibarkh and Monika Raj “Secondary amine selective Petasis (SASP) bioconjugation.” Chemical Science2020, 11, 53-61.

Victor Adebomi, Ryan D. Cohen, Rachel Wills, Holland Andrew Hays Chavers, Gary E. Martin and Monika Raj “CyClick Chemistry for the Synthesis of Cyclic Peptides.” Angew. Chem. Int. Ed. 2019, 131, 19249-19256 (Selected as Hot Paper).

Mahesh Sriram, Kuei-Chen Tang, and Monika Raj “Amide bond activation of biological molecules.” Molecules 2018, 23, 2615. (Invited Review article)

Tiauna S. Howard, Ryan D. Cohen, Ogonna Nwajiobi, Zilma P. Muneeswaran, Yonnette E. Sim, Neelam N. Lahankar, Johannes Yeh, and Monika Raj Amino-acid-catalyzed direct aldol bioconjugation. Org. Lett. 201820, 5344-5347.

Hader E. Elashal, Ryan D. Cohen, Heidi E. Elashal, Chuhan Zong, A. James Link and Monika Raj* “Cyclic and Lasso Peptides: Sequence Determination, Topology Analysis, and Rotaxane FormationAngew. Chem. Int. Ed. 2018, 57 (21), 6150-6154.

 Hader E. Elashal, Ryan D. Cohen, Heidi E. Elashal, and Monika Raj* “Oxazolidinone-Mediated Sequence Determination of One-Bead One-Compound Cyclic Peptide LibrariesOrg. Lett.2018, 20 (8), 2374–2377.

Chuhan Zong, Wai Ling Cheung-Lee, Hader E. Elashal,  Monika Raj and A. James Link* “Albusnodin: an acetylated lasso peptide from Streptomyces albusChem. Commun.2018, 54, 1339-1342.

Hader E. Elashal, Yonnette E. Sim and Monika Raj* “Serine Promoted Synthesis of Peptide Thioester-Precursor on Solid Support for Native Chemical Ligation” Chemical Science2017, 8, 117-123.

Hader E. Elashal, Ryan D. Cohen and Monika Raj* “Fmoc solid-phase synthesis of C-terminal modified peptides by formation of a backbone cyclic urethane moietyChem. Commun.2016, 52, 9699-9702.

Hader E. Elashal and Monika Raj* “Site-selective chemical cleavage of peptide bonds” Chem. Commun., 2016, 52, 6304-6307.

Joseph M. Nalbone, Neelam Lahankar, Lyssa Buissereth, and Monika Raj* “Glutamic Acid Selective Chemical Cleavage of Peptide BondsOrg. Lett.2016, 18 (5), 1186–1189.

Ph.D. and Post Doc. Publications

Huabin Wu, Handoko, Monika Raj and Paramjit S. Arora* “Iterative Design of a Biomimetic Catalyst for Amino Acid Thioester CondensationOrg. Lett.2017, 19 (19), 5122–5125.

Monika Raj, Huabin Wu , Sarah L. Blosser , Marc A. Vittoria , and Paramjit S. Arora “Aldehyde Capture Ligation for Synthesis of Native Peptide BondsJ. Am. Chem. Soc.2015, 137, 6932-6940.

Monika Raj, Brooke N. Bullock and Paramjit Arora “Plucking the high hanging fruit: A systematic approach for targeting protein-protein interactions” Bioorganic and Medicinal Chemistry2013, 21, 4051.

Jaskiran Kaur, Monika Raj, Barry S. Cooperman “Fluorescent labeling of tRNA dihydrouridine residues: mechanism and distribution” RNA2011, 17, 1393.

Monika Raj, Nagarathanam Veerasamy, Vinod K. Singh “Highly enantioselective synthesis of 3-cycloalkanone-3-hydroxy-2-oxindoles: potential anticonvulsants” Tetrahedron Lett2010, 2157.

Monika Raj and Vinod K. Singh “Organocatalytic reactions in water” Commun2009, 6687. Most accessed article in 2009.

Monika Raj, Gopal S. Parashari and Vinod K. Singh “Direct syn– and anti-aldol reaction catalyzed by primary-tertiary diamines-Brønsted acids in aqueous medium” Synth. Catal. 2009, 351, 1284.

Monika Raj, Vishnu Maya, and Vinod K. Singh “Highly efficient small organic molecules for enantioselective direct aldol reaction in both organic & aqueous medium: application in synthesis” Org. Chem2009, 74, 4289.

Vishnumaya, Monika Raj, Vinod K. Singh “Highly enantioselective organocatalytic direct aldol reaction in an aqueous medium” Lett2007, 9, 2583. Highlighted in Synfacts 2007(8): 0875-0875

Monika Raj, Vishnumaya, Sandeep K. Ginotra, Vinod K. Singh “Highly enantioselective direct aldol reaction catalyzed by organic molecules” Lett2006, 8, 4097. Most accessed article in 2006.  Highlighted in Synfacts: Synfacts 2006(10): 1066-1066

Monika Raj, Vishnumaya, Sandeep K. Ginotra, Vinod K. Singh “ Lett2006, 8, 4097. Commercialization of my two organocatalysts by Sigma Aldrich

Book Chapters and Patents

Catalytic Methods in Asymmetric Synthesis: Advanced Materials, Techniques, and Applications” Book Chapter (Monika Raj and Vinod K. Singh 2010 published by John Wiley and Sons).

Monika Raj, Huabin Wu and Paramjit Arora “Aldehyde Capture Ligation for Synthesis of Native Peptide Bonds” US Patent, 2014 submitted.