Independent Publications

Nwajiobi, O.; Verma, A.; Raj, M. Rapid Arene Triazene Chemistry for Macrocyclization. J. Am. Chem. Soc. 2022, 144, 4633-4641.

Tang, K.; Maddox, S.; Backus, K. M.; Raj, M. Tunable Heteroaromatic Azoline thioethers (HAT) for Cysteine Selective Modification and Proteome profiling. Chem. Sci. 2022, 13, 763-774.

Tang, K.; Cao, J.; Boatner, L. M.; Li, L.; Farhi, J.; Houk, K. N.; Spangle, J.; Backus, K. M.; Raj, M. Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew. Chem. Int. Ed. 2022, 61, e202112107.

Adebomi, V.; Sriram, M.; Streety, X.; Raj, M. Metal-Free Selective Modification of Secondary Amides: Application in Late-Stage Diversification of Peptides. Org. Lett. 2021, 23, 6189–6193.

Nwajiobi, O.; Sriram, M.; Streety, X.; Raj, M. Triazination unable selective tagging of secondary amines (TrUSS). Angew. Chem. Int. Ed. 2021, 133, 7420-7428.

Tang, K.; Raj, M. One step azolation strategy for site- and chemo-selective labeling of proteins with mass sensitive probes. Angew. Chem. Int. Ed. 2021, 60, 1797-1805.

Wills, R.; Adebomi, V.; Raj, M. Site selective peptide macrocyclizationChemBioChem. 2020 (Invited Review article)

Wills, R.; Adebomi, V.; Raj, M. Peptide cyclization at high concentrationSynlett 2020,31, 1537-1542. (Invited Review article

Sriram, M.; Adebomi, V.; Raj, M. Bioinspired nitroalkylation for selective protein modification and peptide stapling. Angew. Chem. Int. Ed. 2020, 59, 2793-2801.

Sim, Y. E.; Nwajiobi, O.; Sriram, M.; Cohen, R. D.; Raj, M. Secondary amine selective peptide (SASP) bioconjugation. Chem. Sci. 2020, 11, 53-61.

Adebomi, V.; Cohen, R. D.; Wills, R.; Raj, M. CyClick chemistry for synthesis of cyclic peptides. Angew. Chem. Int. Ed. 2019, 131, 19249-19256.

Sriram, M.; Tang, K.-C.; Raj, M. Amide bond activation of biological molecules. Molecules 2018, 23, 2615. (Invited Review article)

Howard, T. S.; Cohen, R. D.; Nwajiobi, O.; Muneeswaran, Z. P.; Sim, Y. E.; Lahankar, N. N.; Yeh, J.; Raj, M. Amino-acid-catalyzed direct aldol bioconjugation. Org. Lett. 2018, 20, 5344-5347.

Elashal, H. E.; Cohen, R. D.; Elashal, H. E.; Zong, C.; Link, A. J.; Raj, M. Cyclic and lasso peptides: sequence determination, topology analysis, and rotaxane formation. Angew. Chem. Int. Ed. 2018, 57, 6150-6154.

Elashal, H. E.; Cohen, R. D.; Elashal, H. E.; Raj, M. Oxazolidinone-mediated sequence determination of one-bead one-compound cyclic peptide libraries. Org. Lett. 2018, 20, 2374-2377.

Zong, C.; Ling, W.; Lee, C.; Elashal, H. E.; Raj, M. Link, A. J. Albusnodin: an acetylated lasso peptide from Streptomyces albus. Chem. Commun. 2018, 54, 1339-1342.

Elashal, H. E.; Sim, Y. E.; Raj, M. Serine promoted synthesis of peptide thioester-precursor on solid support for native chemical ligation. Chem. Sci. 2017, 8, 117-123.

Elashal, H. E.; Cohen, R. D.; Raj, M. Fmoc solid-phase synthesis of C-terminal modified peptides by formation of a backbone cyclic urethane moiety. Chem. Commun. 2016, 52, 9699-9702

Elashal, H. E.; Raj, M. Site-selective chemical cleavage of peptide bonds. Chem. Commun. 2016, 52, 6304-6307.

Nalbone, J. M.: Lahankar, N.; Buissereth, L.; Raj, M. Glutamic acid selective chemical cleavage of peptide bonds. Org. Lett. 2016, 18, 1186–1189.

Ph.D. and Post Doc. Publications

Wu, H.; Handoko, Raj, M.; Arora, P. S. Iterative design of a biomimetic catalyst for amino acid thioester condensation. Org. Lett. 2017, 19, 5122-5125

Raj, M.; Wu, H.; Blosser, S.; Vittoria, M.; Arora, P. S. Aldehyde capture ligation for synthesis of native peptide bonds. J. Am. Chem. Soc. 2015, 37,6932-6940

Raj, M.; Bullock, B. N.; Arora, P. S. Plucking the high hanging fruit: A systematic approach for targeting protein-protein interactions. Bioorg. Med. Chem. 2013, 21, 4051-4057.

Kaur, J.; Raj, M.; Cooperman, B. S. Fluorescent labeling of tRNA dihydrouridine residues: mechanism and distribution. RNA, 2011, 17, 1393-1400.

Raj, M.; Veerasamy, N.; Singh, V. K. Highly enantioselective synthesis of 3-cycloalkanone-3-hydroxy-2-oxindoles: potential anticonvulsants. Tetrahedron Lett. 2010, 2157-2159.

Raj, M.; Singh, V. K. Organocatalytic reactions in water. Chem. Commun. 2009, 6687-6703.

Raj, M.; Parashari, G. S.; Singh, V. K. Direct syn- and anti-aldol reaction catalyzed by primarytertiary diamines-Brønsted acids in aqueous medium. Adv. Synth. Catal. 2009, 351, 1284-1288.

Raj, M.; Maya, V.; Singh, V. K. Highly efficient small organic molecules for enantioselective direct aldol reaction in both organic & aqueous medium: application in synthesis. J. Org. Chem. 2009, 74, 4289-4297.

Vishnumaya, Raj, M.; Singh, V. K. Highly enantioselective organocatalytic direct aldol reaction in an aqueous medium. Org. Lett, 2007, 9, 2593-2595.

Raj, M.; Vishnumaya, Ginotra, S. K.; Singh, V. K. “Highly enantioselective direct aldol reaction catalyzed by organic moleculesOrg. Lett. 2006, 8, 4097-4099. Most accessed article in 2006.  Highlighted in Synfacts: Synfacts 2006(10): 1066-1066

Raj, M.; Vishnumaya, Sandeep K. Ginotra, Vinod K. Singh “ Lett2006, 8, 4097. Commercialization of my two organocatalysts by Sigma Aldrich

Book Chapters and Patents

Catalytic Methods in Asymmetric Synthesis: Advanced Materials, Techniques, and Applications” Book Chapter (Monika Raj and Vinod K. Singh 2010 published by John Wiley and Sons).

Monika Raj, Huabin Wu and Paramjit Arora “Aldehyde Capture Ligation for Synthesis of Native Peptide Bonds” US Patent, 2014 submitted.